John Worboys has been charged with four sexual offences which involve administering a substance used to render a victim unconscious.
All four relate to separate incidents, which were allegedly committed between 2000 and 2008 in London, Scotland Yard said.
Worboys, who now goes by the name John Radford, was served his papers on Wednesday and will appear in court to face the charges on May 23.
The offences were committed between 2000 and 2008, in London and the charges relate to allegations made in early 2018.
A Crown Prosecution Service spokesman said: “In September 2018, the Crown Prosecution Service received a file of evidence from the Metropolitan Police relating to allegations of non-recent sexual assault and of administering drugs to cause unconsciousness.
“Following a review of the evidence, the CPS has today charged John Radford, formerly known as John Worboys, with four offences.
“The charges are two offences of administering a stupefying or overpowering drug with intent to commit rape or indecent assault contrary to section 22 of the Offences Against the Person Act 1861 and a further two offences of administering a substance with intent to commit a sexual offence contrary to section 61 of the Sexual Offences Act 2003.
“He will appear at Westminster Magistrates’ Court on May 23, 2019.”